Colon cancer, also referred to as colorectal or bowel cancer, is the third most common cancer in the United States.
An adequate amount of vitamin D in the body can help prevent and reduce the risk of this cancer. The sunshine vitamin helps in regulation of the cell growth, fight inflammation and prevent cancer cells from spreading.
In fact, it has been found that colon cancer diagnosis and death rates are lowest in states with the highest mean solar radiation.
One study in 2004, published at the Cancer Epidemiology, Biomarkers & Prevention analyzed several studies and came to the conclusion that 1,25-dihydroxyvitamin D and its precursor, 25-hydroxyvitamin D, may aid in the prevention of colorectal cancer in older women.
A study published in “Cancer Prevention Research” (in year 2011) declares – vitamin D may decrease colon cancer risk by improving differentiation and apoptosis and decreasing proliferation, invasiveness, metastatic potential and angiogenesis.
This study mentions that it is even more significantly associated with reduced rectal cancer risk.
In study published in “Gut” (year 2014), the researchers studied a group of immune system cells called T lymphocytes (or T cells), that can target tumor cells and limit their growth.
The researchers found out that high plasma 25-hydroxyvitamin D level is associated with a lower risk of colorectal cancer with intense immune reaction, supporting a role of vitamin D in cancer immune prevention through tumor-host interaction.
Furthermore, the high levels of vitamin D can improve the response to chemotherapy and targeted anticancer drugs in patients with advanced colon cancer.